José Luis Calvo-Guirado, PhD, DDS, Eur PhD, MS1, Associate Researcher at the Universidad Autónoma de Chile, Director of Calvo-Guirado Dental Implant Institute, Spain
Introduction.
The most worldwide dental procedure is tooth extraction, and teeth are still considered clinical residue and, therefore, are discarded as infectious medical waste in many dental offices.
The human demineralized dentin matrix, from extracted crushed human teeth, was developed in 2008 for its osteoconductive and remodeling capacity inside the bone into the implant dentistry field. Bone and dentin are made up of body fluid (10%), collagen (30%), and hydroxyapatite (60%) by weight1. Dentin is an acellular matrix rich in collagen without vessels, whereas bone is a cellular tissue with vessels. A "Smart Dentin Grinder TM" was designed to grind and classify the extracted teeth into a specific size dentin particle. A chemical cleanser, EDTA, and buffered saline were applied to process the dentin particles in a bacterium free for 8 minutes2-6. This novel procedure is indicated mainly in clinical cases in which teeth must be extracted. The bone graft material derived from the tooth with no antigenicity enhances the remodeling capabilities of the bone7.
References
- Binderman I., Hallel G., Casp N., Yaffe A. A Novel Procedure to Process Extracted Teeth for Immediate Grafting of Autogenous Dentin. J. Interdiscipl. Med. Dent. Sci. 2014;2 doi: 10.4172/2376-032X.1000154.
- Calvo-Guirado JL, Ballester-Montilla A, N De Aza P, Fernández-Domínguez M, Alexandre Gehrke S, Cegarra-Del Pino P, Mahesh L, Pelegrine AA, Aragoneses JM, Maté-Sánchez de Val J. Particulated, Extracted Human Teeth Characterization by SEM⁻EDX Evaluation as a Biomaterial for Socket Preservation: An in vitro Study. Materials (Basel). 2019; 25;12(3):380. doi: 10.3390/ma12030380.
- Calvo-Guirado JL, Maté-Sánchez de Val JE, Ramos-Oltra ML, Pérez-Albacete Martínez C, Ramírez-Fernández MP, Maiquez-Gosálvez M, Gehrke SA, Fernández-Domínguez M, Romanos GE, Delgado-Ruiz RA. The Use of Tooth Particles as a Biomaterial in Post-Extraction Sockets. Experimental Study in Dogs. Dent J (Basel). 2018; 6;6(2):12. doi: 10.3390/dj6020012.
- Calvo-Guirado JL, Cegarra Del Pino P, Sapoznikov L, Delgado Ruiz RA, Fernández-Domínguez M, Gehrke SA. A new procedure for processing extracted teeth for immediate grafting in post-extraction sockets. An experimental study in American Fox Hound dogs. Ann Anat. 2018 ;217:14-23. doi: 10.1016/j.aanat.2017.12.010.
- Pohl S, Binderman I, Tomac J. Maintenance of Alveolar Ridge Dimensions Utilizing an Extracted Tooth Dentin Particulate Autograft and PlateletRich Fibrin: A Retrospective Radiographic ConeBeam Computed Tomography Study. Materials (Basel). 2020 ;29:13(5):1083. doi: 10.3390/ma13051083.
- Calvo-Guirado JL, Garcés-Villalá MA, Mahesh L, De Carlos-Villafranca FA. Effectiveness of chemical disinfection in discarding pathogenic bacteria of human particulate tooth graft: An in vitro study. Indian J Dent Sci 2021; 13: 277-282.
- Calvo-Guirado JL. Temporary implants and particulate dentin graft protecting traditional implants in severe periodontal patient: A case report. Indian J Dent Sci 2021;13:201-204.